CD169 (Sialoadhesin, Siglec-1) (MaxLight 490)
Catalogue Number: 227408-ML490-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™490. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | Cd169|SER|sheep erythrocyte receptor|sialic acid-binding Ig-like lectin 1|sialoadhesin|Siglec-1|Sn |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rat |
| Clone: | MOMA-1 |
| Isotype: | IgG2a |
| Immunogen: | Stromal (reticular) elements from spleen. |
| Application: | FC, IF, IHC |
Description
Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. Recognizes murine CD169, also known as sialoadhesin or Siglec-1. CD169 is a lectin-like receptor expressed by certain populations of macrophages including marginal zone metallophils of the spleen, subcapsular macrophages of lymph nodes and stromal macrophages in bone marrow (Morris et al. 1991). CD169 is a ~185kD sialic acid binding receptor containing 17 immunoglobulin-like domains (Crocker et al. 1992). Expression of CD169 can be induced on macrophages in culture by a serum factor and further modulated by cytokine exposure (McWilliam et al. 1992). Rat anti mouse CD169, has been used for the in vivo depletion of specific macrophage populations (Kraal et al. 1988).
Additional Text
Gene Name
SIGLEC1
Specificity
Recognizes mouse CD169.
Purification
Protein G purified
Uniprot ID
Q62230
Gene ID
20612
Antibody Clonality
Monoclonal
227408-ML490 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations