TNF alpha (PE)

Catalogue Number: 227457-PE-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. Labeled with R-Phycoerythrin (PE).
Type:Monoclonal Primary Antibody - Conjugated
Alias:cachectin|TNF-a|TNF-alpha|tumor necrosis factor|tumor necrosis factor (TNF superfamily, member 2)|tumor necrosis factor alpha|tumor necrosis factor ligand superfamily member 2
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: VPM61
Isotype: IgG2a
Immunogen: Recombinant protein corresponding to sheep TNF alpha
Application: FC, WB, IHC, FLISA

Description

Description: Recognizes sheep tumor necrosis factor (TNF) alpha, a 17.5kD cytokine expressed by many different stimulated cell types including monocytes, macrophages, endothelial cells, fibroblasts and both T and B-lymphocytes. The production of TNF alpha is induced by a variety of factors, dependant upon cell type and includes bacterial toxins, IL-1, PDGF, IFN beta, NGF, oncostatin M and viral infections. The presence of TNF alpha is responsible for diverse immunomodulatory, anti-tumor and toxic effects and under certain conditions is also capable of self-stimulation and inhibition.

Additional Text

Gene Name

TNF

UniProt ID

P23383

Specificity

Recognizes sheep TNF alpha. Species Crossreactivity: bovine.

Purification

Protein A purified

Gene ID

443540

Antibody Clonality

Monoclonal