CD3, epsilon (Cy5)
Catalogue Number: 228084-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, sodium azide. Labeled with Cy5. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Rat |
| Clone: | C363.29B |
| Isotype: | IgG2b |
| Immunogen: | IL-4 producing Th2 cell lines including D10 |
| Application: | FC, IHC |
Description
Description: CD3 a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chain ranging in size from 16-28kD and is closely associated with the T cell antigen receptor (TCR). It is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. The monoclonal antibody recognizes an epitope on the 25kD chain of the CD3/TCR complex. In the presence of Fc receptor-bearing accessory cells, soluble can activate primed and naive T cell in vitro. Immobilized monoclonal antibody can also activate both normal T lymphocytes and cloned T cell lines provided the appropriate accessory signals are present. The monoclonal antibody is cytolytic, easily used for cell surface staining, and a good immunoprecipitating.
Additional Text
Gene Name
CD3E
Gene ID
12501
Specificity
Recognizes mouse CD3.
Uniprot ID
P22646
Purification
Purified
Antibody Clonality
Monoclonal
228084 Datasheet
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