CD33 (gp67, p67, Siglec-3) (PE/Cy5.5)

Catalogue Number: 228092-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in 1ml PBS, sodium azide. Labeled with R-Phycoerythrin (PE/Cy5.5).
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 Tests
Host name: Mouse
Clone: WM53
Isotype: IgG1
Immunogen:
Application: FC

Description

Description: CD33 is a 67kD type I transmembrane glycoprotein and a member of the sialoadhesin family of cell surface receptors. pluripotent stem cells but appears on myelomonocytic precursors after CD34. It then continues to be expressed on both the myeloid and monocyte lineages. While it has been reported that CD33 can function as a sialic acid-dependent cell adhesion molecule, cells expressing CD33 require desialylation before they can bind cells bearing the appropriate sialoglycoconjugates. This suggests that inhibitory cis interactions may regulate or block any adhesion function.

Additional Text

Specificity

Recognizes human CD33.

Purification

Purified

Antibody Clonality

Monoclonal