Catalogue Number: 228092-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in 1ml PBS, sodium azide. Labeled with R-Phycoerythrin (PE/Cy5.5). |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 Tests |
| Host name: | Mouse |
| Clone: | WM53 |
| Isotype: | IgG1 |
| Immunogen: | |
| Application: | FC |
Description: CD33 is a 67kD type I transmembrane glycoprotein and a member of the sialoadhesin family of cell surface receptors. pluripotent stem cells but appears on myelomonocytic precursors after CD34. It then continues to be expressed on both the myeloid and monocyte lineages. While it has been reported that CD33 can function as a sialic acid-dependent cell adhesion molecule, cells expressing CD33 require desialylation before they can bind cells bearing the appropriate sialoglycoconjugates. This suggests that inhibitory cis interactions may regulate or block any adhesion function.
Recognizes human CD33.
Purified
Monoclonal