CD44 (Pgp-1, H-CAM, ECMR-III, HUTCH-1) (PE/Cy7)
Catalogue Number: 228110-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in 1ml PBS, sodium azide. Labeled with R-Phycoerythrin (PE/Cy7). |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 Tests |
| Host name: | Mouse |
| Clone: | F10-44-2 |
| Isotype: | IgG2a |
| Immunogen: | Purified human T cells. |
| Application: | FC |
Description
Description: CD44, also known as phagocytic glycoprotein-1 (Pgp-1), exists as a large number of different isoforms resulting from alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type I transmembrane protein. Other variable isoforms containing glycosaminoglycans have molecular weights ranging from 110-250kD and are widely expressed on hematopoietic and non-hematopoietic cells. CD44 contributes to the adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix. It also plays a functional role in cell migration, lymphocyte homing, and adhesion during hematopoiesis and lymphocyte activation.
Additional Text
Specificity
Recognizes human CD44.
Purification
Purified
Antibody Clonality
Monoclonal
228110 Datasheet
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