CD8 (Cy5)
Catalogue Number: 228163-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, sodium azide. Labeled with Cy5. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | 3-298 |
| Isotype: | IgG2b |
| Immunogen: | Chicken thymocytes. |
| Application: | FC, IHC |
Description
Description: In the chicken the CD8 molecule is present in two forms - (i) a homodimer of two a chains and (ii) a heterodimer of an a chain and a b chain. Chicken CD8 is expressed on approximately 80% of thymocytes, 45% of blood mononuclear cells, and 50% of spleen cells but less than 1% of cells in the bursa and bone marrow.While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8a- and CD8b-chains, a relatively large proportion of the CD8+ TCRgd cells in the spleens of embryos and young chicks express only the a-chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved but there is a population of TCRgd CD8ab cells in the chicken that is not found in rodents. The monoclonal antibody recognizes the CD8a chain of both the chicken and turkey.
Additional Text
Specificity
Recognizes Chicken CD8a. Species Crossreactivity: Turkey
Purification
Purified
Antibody Clonality
Monoclonal
228163 Datasheet
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