CD86 (B7-2, B70, Ly-58) (PE/Cy7)
Catalogue Number: 228172-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, sodium azide. Labeled with R-Phycoerythrin (PE/Cy7). |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Rat |
| Clone: | 2D10 |
| Isotype: | IgG2b |
| Immunogen: | Mouse B cell lymphoma cell line 5C2. |
| Application: | FC |
Description
Description: CD86 (B7-2) is an 80kD type I integral membrane protein and a member of the immunoglobulin superfamily of cell surface receptors. Along with CD80 (B7-1), CD86 participates in T cell costimulation via interaction with CD28 and CD152 (CTLA-4). It is expressed at very low density in normal tissues but is rapidly upregulated on stimulated B cells, monocytes, and dendritic cells. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response.
Additional Text
Specificity
Recognizes mouse CD86.
Purification
Purified
Antibody Clonality
Monoclonal
228172 Datasheet
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