Interleukin-2 (IL-2) (FITC)

Catalogue Number: 228228-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in 1ml PBS, sodium azide. Labeled with Fluorescein isothiocyanate (FITC).
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Rat
Clone: JES6-5H4
Isotype: IgG2b
Immunogen: Recombinant protein corresponding to mouse IL-2 expressed in E. coli.
Application: FC, FLISA

Description

Description: IL-2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cy- tokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.

Additional Text

Specificity

Recognizes mouse Interleukin-2.

Purification

Purified

Antibody Clonality

Monoclonal