Interleukin-2 (IL-2) (PE)

Catalogue Number: 228230-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in 1ml PB, sodium azide.. Labeled with R-Phycoerythrin (PE).
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Rat
Clone: JES6-5H4
Isotype: IgG2b, kappa
Immunogen: Recombinant protein corresponding to mouse IL-2 expressed in E. coli.
Application: FC, FLISA

Description

Description: IL-2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cy- tokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.

Additional Text

Gene Name

IL2

Gene ID

16183

Uniprot ID

P04351

Specificity

Recognizes mouse Interleukin-2.

Purification

Purified

Antibody Clonality

Monoclonal