NK1.1 (Ly-55, CD161b/CD161c) (PE/Cy7)

Catalogue Number: 228248-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, sodium azide. Labeled with R-Phycoerythrin (PE/Cy7).
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: PK136
Isotype: IgG2a
Immunogen: CE mouse spleen enriched for NK-1 cells and bone marrow cells.
Application: FC

Description

Description: NK1.1, a member of the NKR-P1 family of cell surface receptors, is a type II integral membrane glycoprotein with a C-type lectin domain. It is expressed as a disulfide-linked homodimer on all NK cells as well as subsets of thymocytes and peripheral T lymphocytes in selected strains of mice (e.g., C57BL/6, NZB, and CE). NK1.1 mediates cellular activation and differentiation, and is thought to have a particular role in generating Th2 cells. This product does not react with NK cells of BALB/c mice.

Additional Text

Specificity

Recognizes mouse NK1.1.

Purification

Purified

Antibody Clonality

Monoclonal