ORC6L (ORC 6, ORC6, Origin recognition Complex Subunit 6, origin recognition ComplexSubunit 6 Homolog like (yeast), origin recognition Complex Subunit 6 Homolog like 2, originrecognition Complex Subunit 6 like (yeast))
Catalogue Number: 254206-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, 0.09% sodium azide. |
| Type: | ChIP Validated Antibodies |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 ul |
| Host name: | Rat |
| Clone: | 3A4 |
| Isotype: | IgG2a |
| Immunogen: | Full length protein (Human): ORC6L |
| Application: | IP, ChIP, WB |
Description
Description: The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. ORC6L is a subunit of the ORC complex. It has been shown that ORC6L and and ORC1L are loosely associated with the core complex consisting of ORC2L 3L 4L and 5L. Gene silencing studies with small interfering RNA demonstrated that ORC6L plays an essential role in coordinating chromosome replication and segregation with cytokinesis.
Additional Text
Specificity
Recognizes ORC6L. Species Crossreactivity: Human
Purification
Protein G purified
Antibody Clonality
Monoclonal
254206 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations