Catalogue Number: 27139-IBL
|Manufacturer:||IBL - (Immuno-Biologicals Laboratories Co Ltd)|
|Type:||Human ELISA Kit|
|Shipping Condition:||Blue Ice|
|Range:||3.13 ~ 200 pg/mL|
|Sample type:||EDTA-plasma,Serum,Cell culture supernatant|
Description: GROα/MGSA as the CXC subfamily has the high homology with IL-8 in amino acid sequences. It is reported that it also has the similar configuration in 3D structural analysis and the almost same level of leukocyte chemotaxis with IL-8. Production from activated monocyte, fibroblast, epithelial and endothelial cells have been reported. In stomach mucosa infection of helicobacter pylori, individuals who suffer gastritis and ulcer in their stomach show significantly high level of IL-8 and GROα compared to non-infectious group. The GROα is identified as a factor to promote melanoma cell propagation and is a polypeptide with 3 isoforms of α, β, and? γ. The GROα depresses the propagation of endothelial cells. As renal cancer has plenty of tumor blood vessels, it is important to identify the vascular formation factor and GROα is especially important in the formation of blood vessels.
Compound Cross Reactivity Human GROα/MGSA 100.0% Human IL-8 ≤0.1% Human IP-10 ≤0.1% Rat GROα ≤0.1%