Human GROα/MGSA Assay Kit - IBL

Catalogue Number: 27139-IBL

Manufacturer:IBL - (Immuno-Biologicals Laboratories Co Ltd)
Type:Human ELISA Kit
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 96 Well
Range: 3.13 ~ 200 pg/mL
Sensitivity:
Sample type: EDTA-plasma,Serum,Cell culture supernatant
Sample size:

Description

Description: GROα/MGSA as the CXC subfamily has the high homology with IL-8 in amino acid sequences. It is reported that it also has the similar configuration in 3D structural analysis and the almost same level of leukocyte chemotaxis with IL-8. Production from activated monocyte, fibroblast, epithelial and endothelial cells have been reported. In stomach mucosa infection of helicobacter pylori, individuals who suffer gastritis and ulcer in their stomach show significantly high level of IL-8 and GROα compared to non-infectious group. The GROα is identified as a factor to promote melanoma cell propagation and is a polypeptide with 3 isoforms of α, β, and? γ. The GROα depresses the propagation of endothelial cells. As renal cancer has plenty of tumor blood vessels, it is important to identify the vascular formation factor and GROα is especially important in the formation of blood vessels.

Additional Text

Specificity

Compound Cross Reactivity Human GROα/MGSA 100.0% Human IL-8 ≤0.1% Human IP-10 ≤0.1% Rat GROα ≤0.1%

Price
420.00


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