Mouse Leptin Assay Kit - IBL

Catalogue Number: 27160-IBL

Manufacturer:	IBL - (Immuno-Biologicals Laboratories Co Ltd)
Type:	Mouse ELISA Kit
Shipping Condition:	Blue Ice
Storage Condition:	2-8°C
Unit(s):	96 well plate
Range:	12.5 ~ 800 pg/mL
Sensitivity:
Sample type:	Cell Culture Supernatant, Plasma, Serum
Sample size:

Overview
Datasheets

Description

Description: The recessive obesity mutation, ob, identified in 1950, results in profound obesity and type II diabetes as part of a syndrome that resembles morbid obesity in humans. Freidman's group at Rockefeller University originally identified the obesity gene that encodes for Leptin in 1994. Leptin is a 16 KDa secreted protein produced by the ob gene. Adipose tissue produces Leptin and releases it into the bloodstream. As fat deposits grow, blood Leptin levels tends to increase. It has been suggested that Leptin acts as a lipostat, increasing as fat gets deposited into adipocytes. It is also found that the protein acts as a hormone instructing the brain to stop food consumption and to increase activity. The protein has also been shown to signal and probably control the onset of puberty. In addition, recent study shows Leptin acts as a potent inhibitor of bone formation through central nervous system.

27160 Datasheet

Price

£485.00

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