Catalogue Number: 27174-IBL
|Manufacturer:||IBL - (Immuno-Biologicals Laboratories Co Ltd)|
|Type:||Mouse ELISA Kit|
|Shipping Condition:||Blue Ice|
|Range:||21.88 - 1,400 pg/mL|
|Sample type:||Serum, Cell culture supernatant|
Description: Thrombopoietin promotes the growth and differentiation (proliferation) of megakaryocytes which produce platelets. TPOR (Thrombopoietin receptor), which is also called c-MPL (Myeloproliferative leukemia protein) or CD110, is a receptor for thrombopoietin. And it is suggested that TPOR may also play a role in the maintenance of hematopoietic stem cells, which are stem cells located within the bone marrow that have the potential to develop into red blood cells, white blood cells, megakaryocytes and platelets. This receptor is activated when thrombopoietin protein binds to it, and the activated receptor stimulates a signaling pathway called the JAK/STAT pathway, which transmits signals from outside the cell to the cell's nucleus and is important for controlling the production of blood cells. This ELISA kit can measure concentration of mouse soluble c-MPL/TPOR in serum or cell culture supernatant.
Substance Cross Reactivity Mouse c-MPL/TPOR 100.0% Albumin < 0.1 % Transferrin < 0.1 % Immunoglobulin < 0.1 %