Mouse c-MPL/TPOR Assay Kit - IBL

Catalogue Number: 27174-IBL

Manufacturer:IBL - (Immuno-Biologicals Laboratories Co Ltd)
Type:Mouse ELISA Kit
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 96 Well
Range: 21.88 - 1,400 pg/mL
Sensitivity:
Sample type: Serum, Cell culture supernatant
Sample size:

Description

Description: Thrombopoietin promotes the growth and differentiation (proliferation) of megakaryocytes which produce platelets. TPOR (Thrombopoietin receptor), which is also called c-MPL (Myeloproliferative leukemia protein) or CD110, is a receptor for thrombopoietin. And it is suggested that TPOR may also play a role in the maintenance of hematopoietic stem cells, which are stem cells located within the bone marrow that have the potential to develop into red blood cells, white blood cells, megakaryocytes and platelets. This receptor is activated when thrombopoietin protein binds to it, and the activated receptor stimulates a signaling pathway called the JAK/STAT pathway, which transmits signals from outside the cell to the cell's nucleus and is important for controlling the production of blood cells. This ELISA kit can measure concentration of mouse soluble c-MPL/TPOR in serum or cell culture supernatant.

Additional Text

Specificity

Substance Cross Reactivity Mouse c-MPL/TPOR 100.0% Albumin < 0.1 % Transferrin < 0.1 % Immunoglobulin < 0.1 %

Price
531.00


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