Catalogue Number: 27188-IBL
|Manufacturer:||IBL - (Immuno-Biologicals Laboratories Co Ltd)|
|Type:||Human ELISA Kit|
|Shipping Condition:||Blue Ice|
|Unit(s):||96 well plate|
|Range:||20 ~ 1,280 pg/mL|
|Sample type:||Cell Culture Supernatant, Plasma, Serum|
Description: The syndecan family contains four members (syndecan-1/syndecan, syndecan-2/fibroglycan, syndecan-3/N-syndecan, syndecan-4/ryudocan (amphyglycan)), which are transmembrane heparan sulfate proteoglycans (HSPGs). These HSPGs exhibit cell type-specific distribution with vascular endothelial cells expressing syndecan-1, -2, and -4, and predominant targeting to basolateral surfaces. The syndecan family members are type I integral membrane proteins with homologous transmembrane and cytoplasmic domains. The combined transmembrane/cytoplasmic domains contain four well-conserved tyrosine residues, which might serve important roles for biological function. The cytoplasmic tail of syndecan-4 interacts with focal adhesion molecules. Thus, syndecan-4 is known to have various biological functions such as anticoagulation, cell adhesion and cell multiplication. The control set is available for sale on request.