Human DMP1 Assay Kit - IBL
Catalogue Number: 27261-IBL
| Manufacturer: | IBL - (Immuno-Biologicals Laboratories Co Ltd) |
| Type: | Human ELISA Kit |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 96 well plate |
| Range: | 3.6 ~ 230 pmol/L |
| Sensitivity: | |
| Sample type: | Cell Culture Supernatant, Plasma, Serum, Urine |
| Sample size: |
Description
Description: Dentin Matrix Protein 1(DMP1) is a constitutive protein in extracellular matrix of osteocyte and it belongs to Small Integrin-Binding Ligand, N-linked Glycoprotein (SIBLING) family. It is synthesized as a full-length 105kDa proprotein and it is divided into 37kDa at N terminal side and 57kDa at C terminal side in the secretion process. It has a lot of acidic domains and it binds with calcium because of the feature that become negative charged within tissues and it has an important role for bone mineralization. DMP1 expresses in osteocyte while other constitutive proteins in extracellular matrix such as Osteopontin, Osteocalcin and Bone sialoprotein express in osteoblast cells. Osteocyte which is a main constituent cell of bone regulates activities of osteoclastic cells and osteoblast cells and it adjusts bone remodeling process. It also acts as an endocrine cell which secrets FGF-23. DMP1 in blood is considered as a candidate of biomarker which reflects activities of osteocyte and it is also suggested to become useful information for research of bone metabolism and phosphate metabolism. The concentration of DMP1 in human blood can be quantitatively measured by this ELISA kit.
27261 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations