Human c-Met Assay Kit - MCM

Catalogue Number: 27407-IBL

Manufacturer:IBL - (Immuno-Biologicals Laboratories Co Ltd)
Type:Human ELISA Kit
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 96 Well
Range: 0.78 ~ 50 ng/mL
Sensitivity:
Sample type: EDTA-plasma, Serum, Cell culture supernatant
Sample size:

Description

Description: c-Met, the product of c-met gene has been reported to be the HGF receptor since HGF induces phosphorylation of c-Met by binding specifically to it. It is a heterodimer protein composed of an α-chain that is linked to a β-chain. The β-chain has the intracellular tyrosine kinase domain, the transmembrane domain and the extracellular domain, and it is tied into the α-chain that is the extracellular domain of c-Met. c-Met exists mainly in epidermal cells. It is found in the digestive tract, prostate gland, seminal vesicles, mammary gland, microglia cells, monocytes and macrophages, and more amount in the liver and kidney. It is considered that c-Met tansmits signals resulting from binding to HGF, such as growth, motility and organ formation, in the organs and cells mentioned above. This kit is designed to measure Human c-Met.

Additional Text

Specificity

Compound Cross Reactivity Human c-Met 100.0% Human HGF ≤0.1% Human HGFA ≤0.1% Human HAI-1 ≤0.1% Human HAI-2 ≤0.1%

Price
881.00


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