BACE1 Assay Kit 27752
Catalogue Number: 27752-IBL
| Manufacturer: | IBL - (Immuno-Biologicals Laboratories Co Ltd) |
| Type: | Other ELISA Kits |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 96 well plate |
| Range: | 1.56 ~ 100 ng/mL |
| Sensitivity: | |
| Sample type: | Cell Extract, Tissue Extract |
| Sample size: |
Description
Description: Neuropathologically Alzheimer's disease (AD) is characterized by widespread deposition of amyloid β protein (Aβ) in the cerebral cortex, and since the intracerebral accumulation of Aβ is highly specific for AD and the gene mutation responsible for familial amyloidosis causes Aβ to increase, Aβ is thought to be of extremely great significance in the pathogenetic mechanism of AD. Aβ is generated by proteolysis of the Aβ precursor protein (APP), a type I membrane protein. The enzyme that cleaves it at the N-terminal is called β secretase, and it is regarded as being the protease that acts at the initial step in the production of Aβ. The major β secretase has been identified as β-site APP Cleaving Enzyme 1 (BACE1), and BACE2 has been isolated as its homologue. The control set is available for sale on request.
27752 Datasheet
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