Human VEGFR-3/Flt-4 Assay Kit - IBL

Catalogue Number: 27779-IBL

Manufacturer:IBL - (Immuno-Biologicals Laboratories Co Ltd)
Type:Human ELISA Kit
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 96 Well
Range: 0.03 ~ 2 ng/mL
Sensitivity:
Sample type: EDTA-plasma, Serum, Cell culture supernatant
Sample size:

Description

Description: All members of the VEGF family (VEGF-A, -B, -C, -D, -E) stimulate cellular responses by binding to tyrosine kinase receptors (the VEGFRs) on the cell surface, causing them to dimerize and become activated through transphosphorylation. The VEGF receptors have an extracellular portion consisting of 7 immunoglobulin-like domains, a single transmembrane spanning region and an intracellular portion containing a split tyrosine-kinase domain. The VEGFR-3, which is also known as Flt-4 (Fms-like tyrosine kinase 4), has been discovered as a third receptor. It is known that VEGFR-3/Flt-4 mediates lymphangiogenesis in response to VEGF-C and VEGF-D. This product is capable of the determination of human VEGFR-3/Flt-4 in human serum, EDTA-plasma or cell culture supernatant.

Additional Text

Specificity

Compound Cross Reactivity Human VEGF-3/Flt-4 100.0% Human c-Kit ≤0.1 % Human KDR ≤0.1 % Human Tie-2 ≤0.1 % Human PDGFRα ≤0.1 % Human PDGFRβ ≤0.1 %

Price
420.00


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