Anti-Rat C-ERC/Mesothelin (306) Rabbit IgG Affinity Purify 28001
Catalogue Number: 28001-IBL
| Manufacturer: | IBL - (Immuno-Biologicals Laboratories Co Ltd) |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 100 ug, 10 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Synthetic peptide of the part of Rat C-ERC/Mesothelin (GKEPNVVDENLIFYQNWELEA) |
| Application: | WB, IHC |
Description
Description: Erc has been identified as a gene showing stronger expression in cancer-affected renal cell than in normal renal tissue in Eker rats (a rat model of renal cancer). The human homologue of the protein encoded by this gene is called MPF (megakaryocyte potentiating factor) or mesothelin. This protein is detected especially prominently in mesothelial cells, and its involvement has been suggested in the development of mesothelioma, making it a promising tumor marker. In humans, involvement of this protein has also been suggested in the development of pancreatic, ovarian and pulmonary cancers, etc. The protein is expressed as a GPI anchor-type membranous protein (about 71 kDa in molecular weight), which is thought to be digested by a furin-like protease to yield fragments about 31 kDa and 40 kDa in size. We have prepared an antibody specific to C-ERC/Mesothelin (40 kDa fragment). This antibody specifically recognizes rat C-ERC/Mesothelin which is applicable for the analysis of ERC expression in mesothelial cells, tumors, cell lines, etc.
Additional Text
Purification
Affinity Purified
Antibody Clonality
Polyclonal
28001 Datasheet
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