Anti-Human mLST8 (L17) Rabbit IgG Affinity Purify

Catalogue Number: 28013-IBL

Manufacturer:IBL - (Immuno-Biologicals Laboratories Co Ltd)
Physical state:Lyophilized product from 1% BSA in PBS containing 0.05% NaN3
Type:Polyclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ug, 10 ug
Host name:
Immunogen: Synthetic peptide of N-terminal of Human mLST8(TAGYDHTVRFWQAHSGIC)


Description: mLST8 (mammalian lethal with sec-13), an about 39 kDa protein which has WD40 domains, has been identified as a configuration factor of mTORC1/mTOR complex 1 and then found to be also a configuration factor of mTORC2. mLST8 is conserved over species and widely expressed in a variety of cells. It is assumed that mLST8 plays a role in promoting activity of mTOR kinase, for mLST8 binds to the kinase domain of mTOR and phosphorylation of p70 S6 (a substrate of mTOR kinase) decreases by RNAi.


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