Anti-Human Rictor (R1291) Rabbit IgG Affinity Purify 28039
Catalogue Number: 28039-IBL
| Manufacturer: | IBL - (Immuno-Biologicals Laboratories Co Ltd) |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 100 ug, 10 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Synthetic peptide of a part of Human Rictor (GSSHTLPRRAQSLKA) |
| Application: | IP, WB |
Description
Description: Rictor (rapamycin-insensitive companion of mTOR/ mAVO3) is about 200 kDa and identified as an mTOR-binding protein. Rictor is a factor that constitutes a complex with mLST8 and Sin 1 which is called mTORC2 (mTOR complex 2), and it is contrasted with raptor in mTORC1. It has a domain structure which is rather conserved over species, and these are thought to be necessary for formation of mTORC2 and binding to substrates, but then the details of their functions are not clear. Regulation of actin-cytoskeletal organization through mediation of Rho family (low molecular weight GTP-binding protein) and PKCα, and phosphorylation of hydrophobic motif site at the C-terminal of PKB/Akt have been reported as effects of mTORC2 including rictor.
Additional Text
Purification
Affinity Purified
Antibody Clonality
Polyclonal
28039 Datasheet
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