Anti-Human LRG (329) Rabbit IgG Affinity Purify

Catalogue Number: 28085-IBL

Manufacturer:IBL - (Immuno-Biologicals Laboratories Co Ltd)
Type:Polyclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 100 ug, 10 ug
Host name: Rabbit
Isotype: IgG
Immunogen: Synthetic peptide of the C terminal part of Human LRG(CAGPEAVKGQTLLAVAKSQ)
Application: WB, IHC


Description: Among the diseases which should be distinguished from iNPH (idiopathic normal pressure hydrocephalus) of elderly people showing symptoms such as gait disorder and dementia, there are some neurodegenerative diseases such as Alzheimer's disease, FTLD (frontotemporal lobar degeneration) and disorder associated with Parkinson's disease. iNPH can be treated by ventriculo-peritoneal shunt (VP shunt), so a marker in spinal fluid which can distinguish it from neurodegenerative diseases in an early stage has been required. Arai, Miyajima et al. had identified the high level of leucine-rich alpha-2-glycoprotein (LRG) in cerebrospinal fluid of iNPH patients, and they reported that measurement of LRG would be useful for differential identification of iNPH.This antibody can be used for immunostaining of astrocytes in localized site of human brain, cultured human astrocytes and human glioma cells.


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