Anti- GFAT1 (663) Rabbit IgG Affinity Purify

Catalogue Number: 28121-IBL

Manufacturer:IBL - (Immuno-Biologicals Laboratories Co Ltd)
Physical state:Lyophilized product from 1 % BSA in PBS containing 0.05 % NaN3
Type:Polyclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ug, 10 ug
Host name:
Clone:
Isotype:
Immunogen: Synthetic peptide of the C terminal part of GFAT1 (RGYDVDFPRNLAKSVTVE)

Description

Description: GFAT1 (Glutamine : fructose-6-phosphate amidotransferase 1) is one of nutrient- sensitive phosphoprotein which was identified as a protein phosphorylated in glucose-deprived cells. Three nutrient signaling pathways have been widely known; (i) the mammalian target of rapamycin (mTOR) signaling pathway, (ii) AMP-activated protein kinase (AMPK) signaling pathway, and (iii) hexosamine signaling pathway. GFAT1 was isolated, which is the first and rate-limiting enzyme for the entry of glucose into the hexosamine signaling pathway to generate UDP-GlcNAc in mammals. Recent evidences have indicated that the signals derived from nutrients like amino acid and glucose play important roles in the control of the cellular activities as well as in synthesis of proteins and generation of ATP.

Additional Text

Specificity

Cross reacts with mouse and rat.

Price
280.00


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