Catalogue Number: 28125-IBL
|Manufacturer:||IBL - (Immuno-Biologicals Laboratories Co Ltd)|
|Physical state:||Lyophilized product in PBS containing 1 % BSA and 0.05 % NaN3|
|Type:||Polyclonal Primary Antibody - Unconjugated|
|Shipping Condition:||Blue Ice|
|Unit(s):||50 ug, 5 ug|
|Immunogen:||Synthetic peptide of a part of Rat CyCAP (LGRAAFGPGKGPIMLDEVEC)The sequence used is 100% identical with Mouse CyCAP|
Description: CyCAP is a binding protein for cyclophilin C in competition with cyclosporine. It is present in brain, kidney and macrophage cells and is known as an inflammation-related protein. In recent years, it has been reported that CyCAP forms complexes with calcineurin and NFATc1 in macrophages and enhances their phagocytosis activity. CyCAP is detected in macrophages both of in vivo and in vitro, and the signals increase when the macrophages are activated. Additionally, it is stained in neurocytes of rat brain tissues.
Cross reacts with mouse CyCAP.