Anti-GAPDHS Monoclonal Antibody (Clone:Hs-8)
Catalogue Number: 30-1189-ABO
| Manufacturer: | Abeomics |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | GAPDHS||GAPD2||GAPDH2||GAPDS||HSD-35||HSD35 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 0.1 mg |
| Host name: | Mouse |
| Clone: | Hs-8 |
| Isotype: | IgM |
| Immunogen: | Freshly ejaculated human sperms were washed in PBS and extracted in 3% acetic acid, 10% glycerol, 30 mM benzaminidine. The acid extract was dialyzed against 0.2% acetic acid and subsequently used for immunization. |
| Application: | FACS, ICC, WB |
Description
Description: GAPDHS (the sperm-specific glyceraldehyde phosphate dehydrogenase, also known as GAPD2, GAPDS, HSD-35, or GAPDH-2, is a glycolytic enzyme that plays an important role in carbohydrate metabolism. Like its somatic cell counterpart, this sperm-specific enzyme functions in a nicotinamide adenine dinucleotide-dependent manner to remove hydrogen and add phosphate to glyceraldehyde 3-phosphate to form 1,3-diphosphoglycerate. During spermiogenesis, this enzyme may play an important role in regulating the switch between different energy-producing pathways, and it is required for sperm motility and male fertility. It can be used as an intra-acrosomal marker for evaluation of the physiological state of sperm cells as well as for selection of a suitable method of fertilization in the laboratories of assisted reproduction.
Additional Text
Gene Name
GAPDHS
Gene ID
26330
Uniprot ID
O14556
Purification
Purified
Antibody Clonality
Monoclonal
Application Notes
Western Blotting Immunocytochemistry Recommended dilution: Purified Antibody: 10 µg/ml Staining technique: Membrane permeabilization (acetone) is essential. Flow Cytometry
30-1189 Datasheet
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