Anti-Nitrotyrosine Monoclonal Antibody (Clone:EM-30)
Catalogue Number: 30-1495-ABO
| Manufacturer: | Abeomics |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 0.1 mg |
| Host name: | Mouse |
| Clone: | EM-30 |
| Isotype: | IgG1 |
| Immunogen: | NO2-Tyr-CH2-Thyroglobulin |
| Application: | WB, IHC-Fr, IHC |
Description
Description: Nitrotyrosine can be detected in proteins from a variety of tissues usually in association with pathological conditions. Reaction of nitric oxide with superoxide produces peroxynitrite, which can undergo heterolytic cleavage into nitronium and hydroxyl ions. Nitration of tyrosine residues by nitronium ion forms nitrotyrosine groups in the respective proteins. Nitrotyrosine is thus a marker for inflammation-associated tissue damage.
Additional Text
Purification
Protein A purified
Antibody Clonality
Monoclonal
Application Notes
Immunohistochemistry Recommended dilution:10 µg/ml Positive tissue:colon cancer epithelium, prostate hyperplasia
30-1495 Datasheet
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