Catalogue Number: 30-2462-ABO
Manufacturer: | Abeomics |
Type: | Monoclonal Primary Antibody - Unconjugated |
Alias: | MME||EPN |
Shipping Condition: | Blue Ice |
Unit(s): | 100 tests |
Host name: | Mouse |
Clone: | MEM-78 |
Isotype: | IgG1 |
Immunogen: | NALM-6 human pre-B cell line |
Application: | FACS |
Description: CD10 (neutral endopeptidase - NEP, common acute lymphocytic leukemia antigen - CALLA, membrane metallo-endopeptidase - MME, enkefalinase) is a 100-kDa cell surface zinc metalloprotease cleaving peptide bonds on the N-terminus of hydrophobic amino acids and inactivating multiple physiologically active peptids. CD10 is expressed on various normal cell types, including lymphoid precursor cells, germinal center B lymhocytes, and some epithelial cells, and its expression level serves as a marker for diagnostics of many carcinomas. CD10 is also a differentiation antigen for early B-lymphoid progenitors in the B-cell differentiation pathway and has a key role in regulation of growth, differentiation and signal transduction of many cellular systems.
4311
MME
P08473
Monoclonal