PE/DyLight Conjugated, Anti-CD10 / CALLA Monoclonal Antibody (Clone:MEM-78)

Catalogue Number: 30-2462-ABO

Manufacturer:Abeomics
Type:Monoclonal Primary Antibody - Unconjugated
Alias:MME||EPN
Shipping Condition:Blue Ice
Unit(s): 100 tests
Host name: Mouse
Clone: MEM-78
Isotype: IgG1
Immunogen: NALM-6 human pre-B cell line
Application: FACS

Description

Description: CD10 (neutral endopeptidase - NEP, common acute lymphocytic leukemia antigen - CALLA, membrane metallo-endopeptidase - MME, enkefalinase) is a 100-kDa cell surface zinc metalloprotease cleaving peptide bonds on the N-terminus of hydrophobic amino acids and inactivating multiple physiologically active peptids. CD10 is expressed on various normal cell types, including lymphoid precursor cells, germinal center B lymhocytes, and some epithelial cells, and its expression level serves as a marker for diagnostics of many carcinomas. CD10 is also a differentiation antigen for early B-lymphoid progenitors in the B-cell differentiation pathway and has a key role in regulation of growth, differentiation and signal transduction of many cellular systems.

Additional Text

Gene ID

4311

Gene Name

MME

Uniprot ID

P08473

Antibody Clonality

Monoclonal