Anti-DLL4 PE (Clone : MHD4-46)
Catalogue Number: 30-2532-ABO
30-2532 Image
30-2532 Image
Figure 1 : Separation of CHO/DLL4 cells stained using anti-human DLL4 (MHD4-46) PE antibody (10 µl reagent per million cells in 100 µl of cell suspension, red-filled) from CHO/DLL4 cells stained using mouse IgG1 isotype control (MOPC-21) PE antibody (concentration in sample 1 µg/ml, same as CD135 APC concentration, black-dashed) in flow cytometry analysis (surface staining) of CHO/DLL4 cell suspension.
| Manufacturer: | Abeomics |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | Delta like ligand 4, AOS6, canonical Notch ligand 4,delta like canonical Notch ligand 4 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 0.1 mg |
| Host name: | |
| Clone: | MHD4-46 |
| Isotype: | IgG1, kappa |
| Immunogen: | recombinant soluble human DLL4 |
| Application: | FACS |
Description
Description: DLL4 (Delta-like 4) is one of five ligands of Notch receptors. It interacts with Notch1 and Notch4. DLL4 is up-regulated at sites of physiologic and pathologic angiogenesis, whereas its expression is low in most adult normal tissues. It is also highly expressed in human clear-cell renal carcinomas, bladder cancers, and breast cancers. Blocking the DLL4-Notch interaction seems to be a promissing therapeutic approach.Specificity : The mouse monoclonal antibody MHD4-46 recognizes the extracellular domain of DLL4 (Delta-like ligand 4), a type I transmembrane protein which plays an important role in vascular development.
Additional Text
Gene ID
54567
Gene Name
DLL4
Purification
Purified
Antibody Clonality
Monoclonal
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