Anti-TAp63 Purified
Catalogue Number: 30-2718-ABO
| Manufacturer: | Abeomics |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | tumor protein p63 AIS, KET, LMS, NBP, RHS, EEC3, OFC8, SHFM4 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 0.1 mg |
| Host name: | |
| Clone: | TAp63-4.1 |
| Isotype: | |
| Immunogen: | Recombinant human p63 |
| Application: | ICC, IP, WB, IHC |
Description
Description: The p53 family of proteins includes three members, p53, p63, and p73. The protein p63 is encoded by TP63 gene, which gives rise to protein isoforms with different properties and functions due to the presence (TAp63) or absence (deltaNp63) of an N-terminal transactivation domain. Immunohistochemistry of p63 has a clinical relevance for certain tumor types, but investigations have been hampered by a lack of well characterized antibodies that are specific for p63, do not cross-react with the related p53 and p73 proteins, and allow for discrimination between p63 isoforms TAp63 and deltaNp63 with opposite functional properties.Specificity :The mouse monoclonal antibody TAp63-4.1 recognizes TAp63; target epitope LSDPMW. This antibody does not bind to deltaNp63 isoform of p63.
Additional Text
Gene Name
TP63
Gene ID
8626
Uniprot ID
Q9H3D4
Purification
Protein A purified
Antibody Clonality
Monoclonal
Application Notes
Western blotting: Recommended dilution: 1 µg/ml
30-2718 Datasheet
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