Anti-PPM1D Purified
Catalogue Number: 30-2720-ABO
| Manufacturer: | Abeomics |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | protein phosphatase, Mg2+/Mn2+ dependent 1D WIP1, Protein phosphatase 1D, JDVS, WIP1, IDDGIP |
| Shipping Condition: | Blue Ice |
| Unit(s): | 0.1 mg |
| Host name: | |
| Clone: | 7E11/C5 |
| Isotype: | |
| Immunogen: | Purified human PPM1D |
| Application: | ELISA, ICC, WB, IHC |
Description
Description: PPM1D is a Mg2+/Mn2+ dependent protein phosphatase 1D with inducible expression in response to various types of environmental stress. This expression is p53-dependent, and subsequently PPM1D negatively regulates the p53-mediated transcription, thus it suppresses the apoptosis. PPM1D contributes to development of carcinomas, and seems to be a promissing therapeutic target. Amplification of PPM1D is associated with breast cancer.Specificity :The mouse monoclonal antibody 7E11/C5 recognizes an epitope within the sequence FTNEDELYNLLTDSP of PPM1D, a protein phosphatase, which contributes to development of some carcinomas.
Additional Text
Gene ID
8493
Gene Name
PPM1D
Uniprot ID
O15297
Purification
Protein A purified
Antibody Clonality
Monoclonal
Application Notes
Western blotting: Recommended dilution: 1-2 µg/ml.
30-2720 Datasheet
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