HIV-1 (gp41)
Catalogue Number: 301816-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a lyophilized powder in PBS. Reconstitute with 100ul ddH2O. |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Human |
| Clone: | 50-69 |
| Isotype: | IgG1, kappa |
| Immunogen: | Generated from HIV-infected individuals by a method based on the Epstein-Barr virus transformation of peripheral blood mononuclear cells (PBMCs) followed by fusion with heteromyeloma cells. |
| Application: | ELISA |
Description
Description: Of the two types of Human immunodeficiency virus (HIV) which have been characterized, HIV-1 is more infective and is prevalent globally. The HIV virion is encapsulated by a viral envelope that contains complexes of surface proteins, which are important for the virus to attach and fuse to infect target cells. A precursor molecule known as gp160 (glycoprotein 160) is cleaved by proteases into gp120 (glycoprotein 120) and gp41 (glycoprotein 41), glycoproteins that make up the envelope proteins of HIV. Glycoprotein gp41 is embedded in the viral membrane and can interact with other gp41 proteins. The proteins gp41 and gp120 form a complex which is thought to undergo conformational changes in order to initiate membrane fusion of the virus with a cell.
Additional Text
Specificity
Recognizes the HIV-1 protein gp41.
Accession Number
EU794398
Purification
Protein G purified
Antibody Clonality
Monoclonal
301816 Datasheet
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