Activin B Active Recombinant Protein
Catalogue Number: 32-1005-ABO
| Manufacturer: | Abeomics |
| Type: | Other Recombinant Protein |
| Alias: | Inhibin beta B (activin AB beta polypeptide)||Inhibin||beta-2||Activin beta-B chain||MGC157939. |
| Shipping Condition: | RT |
| Unit(s): | 10 ug |
Description
Description: Source : Nicotiana benthamiana plant Activin B human Recombinant produced in Nicotiana benthamiana plant is a beta-B single chain (aa 293-406) containing 123 amino acids (molecular formula C615H910N178O177S12). Activin B is fused to a 10-His-tag at the N-terminal having the total molecular mass of 14kDa & purified by st&ard chromatographic techniques. Inhibins are dimeric peptide hormones produced by female ovarian granulose cells & male Sertoli cells as well as a variety of other tissues. Inhibins have two isoforms, A & B, with the same alpha subunit but different beta subunits. Inhibin A is a dimer of alpha & beta A subunits, inhibin B is a dimer of alpha & beta B subunits.Inhibins are thought to inhibit the production of follicle-stimulating hormone (FSH) by the pituitary gl&. In addition, Inhibins are also thought to play a role in the control of gametogenesis, & embryonic & fetal development.
Additional Text
Application Notes
It is recommended to reconstitute the lyophilized Activin B in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. The biological activity of Activin B is measured by its ability to inhibit mouse plasmacytoma cell line (MPC-11) cells proliferation. EC50 <5ng/ml is required to stimulate a half-maximal response at cytokine saturation. Note: Since applications vary, each investigator should titrate the reagent to obtain optimal results.
32-1005 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations