b NGF CHO Recombinant Protein
Catalogue Number: 32-1093-ABO
| Manufacturer: | Abeomics |
| Type: | Other Recombinant Protein |
| Alias: | Beta Polypeptide||NGF||NGFB||HSAN5||Beta-NGF||MGC161426||MGC161428. |
| Shipping Condition: | RT |
| Unit(s): | 20 ug |
Description
Description: Source : Chinese Hamster Ovary Cells. Nerve Growth Factor-beta Human Recombinant produced in CHO is a noncovalently disulfide linked homodimer, glycosylated, polypeptide chain containing 2 identical 118 amino acids & having a molecular mass of 26.5 kDa.The NGF-b is purified by proprietary chromatographic techniques. NGF-beta has nerve growth stimulating activity & the complex is involved in the regulation of growth & the differentiation of sympathetic & certain sensory neurons. Mutations in this gene have been associated with hereditary sensory & autonomic neuropathy, type 5 (HSAN5), & dysregulation of this gene's expression is associated with allergic rhinitis.
Additional Text
Application Notes
It is recommended to reconstitute the lyophilized NGF-b in sterile 18MO-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. The ED50, calculated by its ability to stimulate chick E9 DRG neurite outgrowth was found to be < 1.0 ng/ml, corresponding to a specific activity of > 1 x 106 units/mg.
32-1093 Datasheet
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