FGF2 Plant Recombinant Protein
Catalogue Number: 32-1168-ABO
| Manufacturer: | Abeomics |
| Type: | Other Recombinant Protein |
| Alias: | Prostatropin||HBGH-2||HBGF-2||FGF-2||FGF-b||Fibroblast growth factor 2||Basic fibroblast growth factor||Heparin-binding growth factor 2. |
| Host Cell: | Oryza Sativa |
| Shipping Condition: | RT |
| Unit(s): | 50 ug |
Description
Description: Source : Rice Grain (Oryza Sativa). FGF-2 Human Recombinant produced in rice is a single, non-glycosylated polypeptide chain containing 146 amino acids & having a molecular mass of ~17kDa.The FGF-b protein is purified by proprietary chromatographic techniques. Basic fibroblast growth factor is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic & cell survival activities, & are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth & invasion. This protein functions as a modifier of endothelial cell migration & proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- & neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Three alternatively spliced variants encoding different isoforms have been described. The heparin-binding growth factors are angiogenic agents in vivo & are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution & concentration of these 2 growth factors.
Additional Text
Application Notes
It is recommended to reconstitute the lyophilized Fibroblast Growth Factor Basic in sterile 18MO-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. The ED50, as calculated by the dose-dependent proliferation of Balb/c 3T3 cells expressing FGF receptors is 1 x106 Units/mg.
32-1168 Datasheet
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