Catalogue Number: 32-1252-ABO
Manufacturer: | Abeomics |
Type: | Other Recombinant Protein |
Alias: | CSF-3||MGI-1G||GM-CSF beta||Pluripoietin||Filgrastim||Lenograstim||G-CSF||MGC45931||GCSF. |
Shipping Condition: | RT |
Unit(s): | 10 ug |
Description: Source : Chinese Hamster Ovary Cells (CHO). Granulocyte Colony Stimulating Factor Human Recombinant produced in CHO cells is a single, glycosylated, polypeptide chain containing 174 amino acids & having a molecular mass of approximately 18 kDa.G-CSF is purified by proprietary chromatographic techniques. Granulocyte Colony Stimulating Factor is a growth factor &/or cytokine produced by the endothelium, macrophages & a number of other immune cells. GCSF stimulates the bone marrow to produce granulocytes & also to stimulate the survival, proliferation, differentiation & function of neutrophil granulocyte progenator cells & mature neutrophils.
It is recommended to reconstitute the lyophilized Granulocyte Colony Stimulating Factor in sterile 18MO-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. The ED50, calculated by the dose-dependant proliferation of murine NFS-60 indicator cells (measured by 3H-thymidine uptake) is < 0.07 ng/ml, corresponding to a Specific Activity of 1.27 x 108 IU/mg.