GH Plant Recombinant Protein
Catalogue Number: 32-1260-ABO
| Manufacturer: | Abeomics |
| Type: | Other Recombinant Protein |
| Alias: | GH1||GH||GHN||GH-N||hGH-N,Pituitary growth hormone||Growth hormone 1||Somatotropin. |
| Shipping Condition: | RT |
| Unit(s): | 10 ug |
Description
Description: Source : Nicotiana benthamiana plant. GH human Recombinant produced in Nicotiana benthamiana plant is a single chain containing 205 amino acids (molecular formula C1025H1570N280O306S7) & 6-His-tag at the N-terminal having the total molecular mass of 22.9kDa. GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity & potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency & short stature.
Additional Text
Application Notes
It is recommended to reconstitute the lyophilized GH in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. The biological activity of human Growth Hormone is measured by cell proliferation using Nb2-11 cells. ED50 < 0.04-0.1 ng/mL.
32-1260 Datasheet
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