Catalogue Number: 32-1301-ABO
Manufacturer: | Abeomics |
Type: | Other Recombinant Protein |
Alias: | Scatter Factor (SF)||Hepatopoietin (HPTA)||HGF. |
Host Cell: | CHO |
Shipping Condition: | RT |
Unit(s): | 10 ug |
Description: Source : Chinese Hamster Ovary Cells. Hepatocyte Growth Factor Human Recombinant produced in CHO is a heterodimer, non-glycosylated, polypeptide chain consisting an a-chain of 463 amino acids & b-chain of 234 having a total molecular mass of 75kDa.The HGF is purified by proprietary chromatographic techniques. Hepatocyte Growth Factor (HGF) is a multifunctional growth factor which regulates both cell growth & cell motility. It exerts a strong mitogenic effect on hepatocytes & primary epithelial cells. HGF synergizes with Interleukin-3& GM-CSFto stimulate colony formation of hematopoietic progenitor cells in vitro & may, therefore, also modulate hematopoiesis.
It is recommended to reconstitute the lyophilized Hepatocyte Growth Factor in sterile 18MO-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. The ED50, calculated by the dose-dependant proliferation of monkey 4MBr-5 indicator cells was found to be 20-40 ng/ml.