OPG Hi-5 Recombinant Protein
Catalogue Number: 32-1642-ABO
| Manufacturer: | Abeomics |
| Type: | Other Recombinant Protein |
| Alias: | TNFRSF11B||OPG||OCIF||Osteoclastogenesis inhibitory factor||Osteoprotegerin||TR1||MGC29565. |
| Shipping Condition: | Blue Ice |
| Unit(s): | 10 ug |
Description
Description: Source : Hi-5. Recombinant Osteoprotegerin produced in baculovirus is a signle, glycosylated polypeptide chain containing 398 amino acid residues (22-401 a.a.), having a calculated molecular mass of 45.6 kDa. The Osteoprotegerin is fused to 17 amino acid His tag at C-terminus amd purified by proprietary chromatographic techniques. Osteoprotegerin acts as decoy receptor for rankl & thereby neutralizes its function in osteoclastogenesis. OPG inhibits the activation of osteoclasts & promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local rankl/opg ratio. Osteoprotegerin may also play a role in preventing arterial calcification. May act as decoy receptor for trail & protect against apoptosis. Trail binding blocks the inhibition of osteoclastogenesis.
32-1642 Datasheet
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