PIP Native Protein

Catalogue Number: 32-1694-ABO

Manufacturer:Abeomics
Type:Other Native Protein
Alias:Prolactin-inducible protein||Gross cystic disease fluid protein 15||GCDFP-15||Prolactin-induced protein||Secretory actin-binding protein||SABP||gp17||PIP||GCDFP15||GPIP4.
Shipping Condition:Dry Ice
Unit(s): 10 ug

Description

Description: Source : Human Seminal Plasma. The Prolactin-Induced Protein produced from Human Seminal Plasma has a molecular mass of 13.52kDa (calculated without glycosylation) containing 118 amino acid residues. Prolactin inducible protein (PIP) is a 17kDa glycoprotein existing in human seminal plasma. PIP is synthesized as a 146 amino acid long polypeptide exhibiting high sequence similarity with mouse submaxillary gl& with a single glycosylation site. The precise biological functions of PIP are still ambiguous but various functions have been assigned to PIP due its existence at high concentration in biological fluids. PIP binds to various proteins such as fibrinogen, actin, keratin, myosin & tropomyosin. PIP is also expressed in pathological conditions of the mammary gl& & in some exocrine tissues, such as the lacrimal, salivary & sweat gl&s. Due to PIP's association with secretory cell differentiation, it has been used in diagnostic evaluation of tumors of breast, salivary gl&, & skin.

Additional Text

Application Notes

It is recommended to add deionized water to prepare a working stock solution of approximately 0.5 mg/ml & let the lyophilized pellet dissolve completely. PIP is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.