SCF Sf9 Recombinant Protein
Catalogue Number: 32-1746-ABO
| Manufacturer: | Abeomics |
| Type: | Other Recombinant Protein |
| Alias: | Kit lig& Precursor||C-kit lig&||SCF||Mast cell growth factor||MGF||SF||KL-1||Kitl||DKFZp686F2250. |
| Host Cell: | Sf9 |
| Shipping Condition: | RT |
| Unit(s): | 10 ug |
Description
Description: Source : Sf9, Insect Cells. Stem Cell Factor Human Recombinant produced in insect cells is a single, glycosylated polypeptide chain containing 165 amino acids & having a molecular mass of 18409 Dalton. The SCF is fused to a C-terminal His-tag (6x His) & purified by proprietary chromatographic techniques. Stem cell factor / KIT lig& (SCF) is a cytokine which binds CD117(c-Kit). SCF is also known as 'steel factor' or 'c-kit lig&'. SCF exists in two forms, cell surface bound SCF & soluble (or free) SCF. Soluble SCF is produced by the cleavage of surface bound SCF by metalloproteases.SCF is a growth factor important for the survival, proliferation, & differentiation of hematopoietic stem cells & other hematopoietic progenitor cells. One of its roles is to change the BFU-E (burst-forming unit-erythroid) cells, which are the earliest erythrocyte precursors in the erythrocytic series, into the CFU-E (colony-forming unit-erythroid).
Additional Text
Application Notes
It is recommended to reconstitute the lyophilized Stem Cell Factor in 10mM acetic acid not less than 100µg/ml, which can then be further diluted to other aqueous solutions. The ED50 as determined by the dose-dependent stimulation of Human TF-1 cells is typically 1-5 ng/ml.
32-1746 Datasheet
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