TGF beta 1 Native Protein
Catalogue Number: 32-1765-ABO
| Manufacturer: | Abeomics |
| Type: | Other Native Protein |
| Alias: | Transforming growth factor beta-1||TGF-beta-1||CED||DPD1||TGFB||TGF-b 1. |
| Host Cell: | Human platelets |
| Shipping Condition: | RT |
| Unit(s): | 2.5 ug |
Description
Description: Source : Human Platelets. Human Transforming Growth Factor-beta 1 purified from Human Platelets having a molecular mass of 25kDa.The TGF-b 1 is purified by proprietary chromatographic techniques. Transforming growth factor betas (TGF Betas) mediate many cell-cell interactions that occur during embryonic development. Three TGFBetas have been identified in mammals. TGFBeta1, TGFBeta2 & TGFBeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule.
Additional Text
Application Notes
It is recommended to reconstitute lyophilized TGF-beta 1 in 0.5% BSA in 0.1N acetic acid, which can then be further diluted to the desired aliquot with 30% acetonitrile & 0.1% trifluoroacetic acid. Stimulates the growth of NRK-1 cells in soft agar at concentrations ranging from 0.1 to 5ng/ml corresponding to a specific activity of 200,000-10,000,000IU/mg. Effective concentration ranges must be experimentally determined. Purified EGF &/or TGF- must be present for observation of the biological activity.
32-1765 Datasheet
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