TGF beta 2 Recombinant Protein
Catalogue Number: 32-1769-ABO
| Manufacturer: | Abeomics |
| Type: | Other Recombinant Protein |
| Alias: | Transforming growth factor||beta 2||cetermin||Glioblastoma-derived T-cell suppressor factor||polyergin||G-TSF||TGF-beta2||TGF-beta-2||transforming growth factor beta-2||BSC-1 cell growth inhibitor||TGFB-2. |
| Shipping Condition: | RT |
| Unit(s): | 5 ug |
Description
Description: Source : Nicotiana benthamiana. TGFB2 Human Recombinant produced in plants is a homodimeric polypeptide chain containing 2 x 118 amino acids & having a total molecular mass of 27.08kDa. The TGFB2 is fused to 6xHis Tag at N-terminus & purified by proprietary chromatographic techniques. TGFB2 is a 27.08 kDa protein having two identical 118 amino acid peptide chains linked by a single disulfide bond. TGFB2 is part of a family of five related cytokines that have an extensive variation of normal & neoplastic cells, indicating the importance of these homo-dimmer proteins as multi-functional regulators of cellular activity. The three mammalian isoforms of TGF- Beta (TGFb1, TGFb2 & TGFb3) signal through the same receptor & stimulate similar biological responses. They are involved in physiological processes as embryogenesis, tissue remodelling & wound healing.
Additional Text
Application Notes
It is recommended to reconstitute the lyophilized TGFB2 in sterile 18M-cm H2O not less than 1µg/40µl, which can then be further diluted to other aqueous solutions. The biological activity of TGFB2 is measured in culture by its ability to inhibit the mink lung epithelial (Mv1Lu) cells proliferation. ED50 < 40ng/ml, corresponding to a specific activity of 25,000 units/mg.
32-1769 Datasheet
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