TNFRSF14 Recombinant Protein
Catalogue Number: 32-1806-ABO
| Manufacturer: | Abeomics |
| Type: | Other Recombinant Protein |
| Alias: | Tumor Necrosis Factor Receptor Superfamily Member 14||HVEM||TR2||Herpes Virus Entry Mediator A||Tumor Necrosis Factor Receptor-Like 2||Herpesvirus Entry Mediator||HVEA||ATAR||CD270||LIGHTR||CD40-Like Protein||Tumor Necrosis Factor Receptor-Like Gene2 |
| Shipping Condition: | RT |
| Unit(s): | 100 ug |
Description
Description: Source : Pichia Pastoris. TNFRSF14 Human Recombinant produced in Pichia Pastoris is a single, glycosylated, polypeptide chain containing 396 amino acids & having a molecular mass of 58.0kDa. However, TNFRSF14 migrates with an apparent molecular mass of 70 kDa in SDS-PAGE under reducing conditions. TNFRSF14, a member of the TNF receptor superfamily, is a type I transmembrane protein. TNFRSF14 is expressed in peripheral blood T cells, B cells, monocytes & in various tissues enriched in lymphoid cells. TNFRSF14 operates as a co-stimulatory factor for the activation of lymphoid cells & as a deterrent to infection by herpesvirus. Additionally, TNFRSF14 encourages the proliferation of T cells, & triggers apoptosis of various tumor cells.
Additional Text
Application Notes
It is recommended to reconstitute the lyophilized TNFRSF14 in sterile 18MO-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. Fully biologically active when compared to st&ard. The biologically active as determined by its ability to inhibit TNF-beta -mediated cytotoxicity using murine L929 cells.
32-1806 Datasheet
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