CDK2 Recombinant Protein

Catalogue Number: 32-2961-ABO

Manufacturer:Abeomics
Type:Other Recombinant Protein
Alias:Cyclin-Dependent Kinase 2||Cell Division Protein Kinase 2||P33 Protein Kinase||EC 2.7.11.22||CDKN2||Cdc2-Related Protein Kinase||P33(CDK2), EC 2.7.11||Cyclin-dependent kinase 2.
Shipping Condition:Blue Ice
Unit(s): 10 ug

Description

Description: Source : Sf9, Baculovirus cells. CDK2 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 306 amino acids (1-298a.a.) and having a molecular mass of 34.9kDa. CDK2 is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques. Cyclin-dependent kinase 2 (CDK2) belongs the Ser/Thr protein kinase family. CDK2 is highly parallel to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. CDK2 is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is limited to the G1-S phase, and is vital for cell cycle G1/S phase transition. The CDK2 protein associates with and is regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). CDK2 activity is also regulated by protein phosphorylation.