ANXA2 Native Protein
Catalogue Number: 32-3197-ABO
| Manufacturer: | Abeomics |
| Type: | Other Native Protein |
| Alias: | ANX2||ANX2L4||CAL1H||LIP2||LPC2||LPC2D||P36||PAP-IV||ANXA2||Annexin A2||Annexin-2||Annexin II||Lipocortin II||Calpactin-1 heavy chain||Calpactin I heavy chain||Chromobindin-8||p36||Protein I||Placental anticoagulant protein IV. |
| Shipping Condition: | Dry Ice |
| Unit(s): | 5 ug |
Description
Description: Source : Human Adipose Tissue. The Human Annexin A2 produced from Human Adipose Tissue has a molecular mass of 38.472kDa (calculated without glycosylation) containing 338 amino acid residues. ANXA2 is part of the annexin family and is involved in the regulation of cellular growth and in signal transduction pathways. ANXA2 protein functions as an autocrine factor which increases osteoclast formation and bone resorption. ANXA2 is associated with sickle cell osteonecrosis. Reduced ANXA2 expression is associated with osteosarcoma metastases. ANXA2 is part of the putative cell surface vitamin D binding protein binding site complex and functions to mediate the chemotactic cofactor effect. ANXA2 is involved in dysferlin deficiency and in muscular dystrophies. Human colon adenocarcinoma cell differentiation is related with an up-regulation of ANXA2.
Additional Text
Application Notes
It is recommended to add deionized water to prepare a working stock solution of approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
32-3197 Datasheet
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