Human Lactoferrin (Breast Milk)

Catalogue Number: 32-4135-ABO

Manufacturer:	Abeomics
Type:	Glycoproteins
Alias:	Lactotransferrin\|\|Lactoferrin\|\|Growth-inhibiting protein 12\|\|Talalactoferrin\|\|LTF\|\|GIG12\|\|LF\|\|HLF2\|\|Neutrophil Lactoferrin.
Shipping Condition:	Dry Ice
Unit(s):	200 ug

Overview
Datasheets

Description

Description: Source : Human breast milk. The Human Lactoferrin produced from Human breast milk has a molecular mass of 76.165kDa (calculated without glycosylation) containing 691 amino acid residues. Lactoferrin is a glycoprotein that belongs to the transferrin family of iron binding proteins. It is found in human breast milk as well as most epithelial surface secretions including tears, nasogastric, saliva, and bronchial. Lactoferrin binds 2 molecules of iron with very high affinity. Lactoferrin inhibits bacterial growth by withholding iron, its N-terminal region is an antimicrobial peptide. Lactotransferrin acts synergistically with lysozyme to potentiate the activity of both proteins. The multifunctional protein lactoferrin has many physiological possible roles. It is often referred to as an innate defense protein and frequently serves as the first line of defense in protection against pathogens. It has been shown to have the ability to bind iron, it is a natural anti-bacterial, anti-fungal and anti-viral, it is an antioxidant and it also has immunomodulatory properties. It has many beneficial properties, which make it a good candidate for a number of product applications. Considerable research is currently going on to explain the various suggested biological functions of lactoferrin.

Additional Text

Application Notes

It is recommended to add deionized water to prepare a working stock solution of approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

32-4135 Datasheet

Price

£373.00

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