Catalogue Number: 32-4415-ABO
Manufacturer: | Abeomics |
Type: | Other Recombinant Protein |
Alias: | Programmed cell death 1 ligand 2||PD-1 ligand 2||PD-L2||PDCD1 ligand 2||Programmed death ligand 2||PDCD1LG2||B7-DC||Butyrophilin B7-DC||CD273||B7DC||CD273||PDCD1L2||PDL2||bA574F11.2||Btdc. |
Shipping Condition: | Blue Ice |
Unit(s): | 25 ug |
Description: Source : E.coli. PDCD1LG2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 204 amino acids (20-200 a.a.) and having a molecular mass of 22.8kDa.PDCD1LG2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Programmed cell death 1 ligand 2 (PDCD1LG2) which takes part in the costimulatory signal, is necessary for T-cell proliferation. PDCD1LG2 is also involved in IFNG production in a PDCD1-independent way. The interaction with PDCD1 inhibits T-cell proliferation by preventing cytokine production and cell cycle progression.