Recombinant Human Transcription Elongation Factor B Polypeptide 1
Catalogue Number: 32-5050-ABO
| Manufacturer: | Abeomics |
| Type: | Other Recombinant Protein |
| Alias: | Transcription elongation factor B polypeptide 1||Elongin 15 kDa subunit||Elongin-C||EloC||RNA polymerase II transcription factor SIII subunit C||SIII p15||TCEB1||SIII. |
| Host Cell: | E. Coli |
| Shipping Condition: | Blue Ice |
| Unit(s): | 20 ug |
Description
Description: Source : Escherichia Coli. TCEB1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 132 amino acids (1-112 a.a.) and having a molecular mass of 14.6kDa. TCEB1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. TCEB1 (elongin C) is a subunit of elongin, which is a common transcription elongation factor that increases the RNA polymerase II transcription elongation past template encoded arresting sites. The SIII complex is comprised of elongins A/A2, B and C. The SIII complex activates elongation by RNA polymerase II by curbing transient pausing of the polymerase at numerous sites within transcription units. Elongin A acts as the transcriptionally active component of the SIII complex, while elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and able to forming a stable complex with elongins B and C. The VHL (von Hippel-Lindau) tumor suppressor protein binds to elongins B and C, and thus inhibits transcription elongation.
32-5050 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations