Recombinant Human TEN1
Catalogue Number: 32-5057-ABO
| Manufacturer: | Abeomics |
| Type: | Other Recombinant Protein |
| Alias: | TEN1 telomerase capping complex subunit homolog (S. cerevisiae)||C17orf106||CST complex subunit TEN1||Protein telomeric pathways with STN1 homolog||Telomere length regulation protein TEN1 homolog||TEN1. |
| Shipping Condition: | Blue Ice |
| Unit(s): | 10 ug |
Description
Description: Source : Escherichia Coli. TEN1 Human Recombinant produced in E. coli is a single polypeptide chain containing 146 amino acids (1-123) and having a molecular mass of 16.2kDa. TEN1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. TEN1 is part of a complex that binds to single-stranded DNA and is necessary in order to protect telomeres from DNA degradation (CST complex). The CST complex binds single-stranded DNA with high affinity in a sequence-independent mode, while isolated subunits bind DNA with low affinity by themselves. Further to telomere protection, the CST complex has most likely a more general part in DNA metabolism at non-telomeric sites.
32-5057 Datasheet
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